{
  "id": "SCR-LIP-000020",
  "statement": "Thyroid disorders may be more frequent in lipedema than in lymphedema, with a cross-sectional cohort reporting thyroid disease in 24.4% of lipedema vs 14.89% of lymphedema patients.",
  "statement_pt": "Distúrbios tireoidianos podem ser mais frequentes no lipedema que no linfedema, com coorte transversal relatando doença tireoidiana em 24,4% (lipedema) vs 14,89% (linfedema).",
  "claim_type": "epidemiologic",
  "context": {
    "population": "women with lipedema vs lymphedema (cross-sectional)",
    "condition": "lipedema",
    "exposure": "lipedema",
    "comparator": "lymphedema patients",
    "outcome": "thyroid disorder prevalence",
    "scope": "comparative prevalence, single cohort"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.3390/jcm14207195",
      "stance": "supporting",
      "study_design": "cross_sectional",
      "n": 716,
      "risk_of_bias": "moderate",
      "year": 2025,
      "amato_authored": false,
      "note": "Fiengo & Sbarbati; 24.4% vs 14.89%"
    }
  ],
  "relations": [
    {
      "type": "associates",
      "target_hint": "thyroid disease"
    }
  ],
  "gaps": "Thyroid disorder not Hashimoto-specific; single cohort, no age/BMI adjustment; not Amato-authored.",
  "primary_amato_source": "DOI:10.3390/jcm14207195",
  "curators": [
    {
      "name": "Alexandre C. M. Amato",
      "orcid": "0000-0003-4008-4029",
      "role": "lead_curator"
    }
  ],
  "created": "2026-05-30",
  "updated": "2026-05-30",
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000007",
      "role": "supporting",
      "question": "Is lipedema associated with thyroid disease?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000007.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000020.html"
}