{
  "id": "SCR-LIP-000022",
  "statement": "Knee pain is a common musculoskeletal feature of lipedema, reported by 58.1% of women screening positive for lipedema in a Brazilian population study.",
  "statement_pt": "A dor no joelho é característica musculoesquelética comum do lipedema, relatada por 58,1% das mulheres com triagem positiva em estudo populacional brasileiro.",
  "claim_type": "clinical_association",
  "context": {
    "population": "Brazilian women screening positive for lipedema",
    "condition": "lipedema",
    "exposure": "lipedema",
    "comparator": "",
    "outcome": "self-reported knee pain",
    "scope": "musculoskeletal symptom prevalence"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1590/1677-5449.202101981",
      "stance": "supporting",
      "study_design": "cross_sectional",
      "n": 253,
      "risk_of_bias": "moderate",
      "year": 2022,
      "amato_authored": true,
      "note": "58.1% knee pain in screen-positive women"
    }
  ],
  "relations": [
    {
      "type": "associates",
      "target_hint": "knee/patellofemoral pain"
    }
  ],
  "gaps": "Self-reported via screening questionnaire; no imaging confirmation; no BMI-matched comparator.",
  "primary_amato_source": "DOI:10.1590/1677-5449.202101981",
  "curators": [
    {
      "name": "Alexandre C. M. Amato",
      "orcid": "0000-0003-4008-4029",
      "role": "lead_curator"
    }
  ],
  "created": "2026-05-30",
  "updated": "2026-05-30",
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000008",
      "role": "supporting",
      "question": "Is lipedema associated with fibromyalgia and other chronic-pain conditions?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000008.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000022.html"
}