{
  "id": "SCR-LIP-000047",
  "statement": "Lipedema can negatively impact mental health and quality of life, and delayed diagnosis or late treatment worsens symptom burden and psychological well-being.",
  "statement_pt": "O lipedema pode impactar negativamente a saúde mental e a qualidade de vida, e o diagnóstico ou tratamento tardio agrava a carga de sintomas e o bem-estar psicológico.",
  "claim_type": "clinical_association",
  "context": {
    "population": "patients with lipedema",
    "condition": "lipedema",
    "exposure": "lipedema (and diagnostic delay)",
    "comparator": "",
    "outcome": "mental health and quality of life",
    "scope": "social/psychological aspects (consensus)"
  },
  "knowledge_state": "probable",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1590/1677-5449.202301832",
      "stance": "supporting",
      "study_design": "consensus",
      "n": 113,
      "risk_of_bias": "moderate",
      "year": 2025,
      "amato_authored": true,
      "note": "consensus agreement 4.66 (mental health/QoL impact) and 4.45 (delayed diagnosis worsens burden), level B/C"
    }
  ],
  "relations": [
    {
      "type": "associates",
      "target_hint": "mental health / quality of life"
    }
  ],
  "gaps": "Psychosocial impact endorsed by consensus; not measured with validated instruments in this statement.",
  "primary_amato_source": "DOI:10.1590/1677-5449.202301832",
  "curators": [
    {
      "name": "Alexandre C. M. Amato",
      "orcid": "0000-0003-4008-4029",
      "role": "lead_curator"
    }
  ],
  "created": "2026-05-30",
  "updated": "2026-05-30",
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000015",
      "role": "context",
      "question": "What is the recommended overall management of lipedema?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000015.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000047.html"
}