{
  "id": "SCR-LIP-000077",
  "statement": "In a survey of 209 German female lipedema patients who underwent liposuction, the average age was 38.5 years, first manifestation occurred at age 16, and diagnosis took a mean of 15 years to achieve, with comorbidities including hypothyroidism (35.9%) and depression (23.0%) at rates exceeding general population prevalence.",
  "statement_pt": "Em uma pesquisa com 209 pacientes alemãs com lipedema submetidas à lipoaspiração, a idade média era de 38,5 anos, a primeira manifestação ocorreu aos 16 anos e o diagnóstico levou em média 15 anos para ser alcançado, com comorbidades incluindo hipotireoidismo (35,9%) e depressão (23,0%) em taxas superiores à prevalência da população geral.",
  "claim_type": "clinical_association",
  "context": {
    "population": "—",
    "condition": "lipedema",
    "exposure": "—",
    "comparator": "—",
    "outcome": "—",
    "scope": "auto-ingested from Layer 1 surveillance"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1097/prs.0000000000006280",
      "stance": "context",
      "study_design": "cross_sectional",
      "n": null,
      "risk_of_bias": "unknown",
      "year": 2019,
      "amato_authored": false,
      "note": "The article provides descriptive epidemiological data on lipedema patients (exclusively female, average age, age of onset, time to diagnosis), which is relevant to who lipedema affects, but the sample is limited to postoperative patients in",
      "title": "New Insights on Lipedema: The Enigmatic Disease of the Peripheral Fat",
      "authors": "Bauer et al.",
      "journal": "Plastic & Reconstructive Surgery"
    }
  ],
  "relations": [],
  "gaps": "Auto-ingested single source; not yet human-reviewed.",
  "primary_amato_source": null,
  "curators": [],
  "provenance": {
    "auto": true,
    "engine": "anthropic/claude-sonnet-4.6",
    "question": "SQ-LIP-000002",
    "source": "europepmc",
    "ingested": "2026-05-31"
  },
  "created": "2026-05-31",
  "updated": "2026-05-31",
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000002",
      "role": "context",
      "question": "How common is lipedema, and who does it affect?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000002.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000077.html"
}