{
  "id": "SCR-LIP-000158",
  "statement": "In 191 women with stage 3 lower-limb lipedema, a standardized two-stage lymph-sparing VASER ultrasound-assisted liposuction protocol reduced mean total limb circumference by 6.40 cm and mean VAS symptom score from 6.04 to 3.17 (p<0.001), with 89.8% patient satisfaction and complications including seroma (5.75%), skin necrosis (2.09%), and transfusion (3.14-4.18%).",
  "statement_pt": "Em 191 mulheres com lipedema de membros inferiores tipo 3, um protocolo padronizado em dois tempos de lipoaspiração assistida por ultrassom (VASER) poupadora de linfáticos reduziu a circunferência total média dos membros em 6,40 cm e o escore médio de sintomas EVA de 6,04 para 3,17 (p<0,001), com 89,8% de satisfação das pacientes e complicações incluindo seroma (5,75%), necrose cutânea (2,09%) e transfusão (3,14-4,18%).",
  "claim_type": "clinical_association",
  "context": {
    "population": "—",
    "condition": "lipedema",
    "exposure": "—",
    "comparator": "—",
    "outcome": "—",
    "scope": "auto-ingested from Layer 1 surveillance"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1097/prs.0000000000012217",
      "stance": "supporting",
      "study_design": "case_series",
      "n": null,
      "risk_of_bias": "unknown",
      "grade": "low",
      "year": 2025,
      "amato_authored": false,
      "note": "Observational single-arm study of 191 patients reporting significant reductions in circumference and pain plus complication rates, directly supporting liposuction efficacy and safety for lipedema; no control group and short 6-month follow-u",
      "title": "Observational Study of Ultrasound-Assisted Liposuction for Lower Limb Lipedema on 191 Female Patients",
      "authors": "Hersant et al.",
      "journal": "Plastic &amp; Reconstructive Surgery"
    }
  ],
  "relations": [],
  "gaps": "Auto-ingested single source; not yet human-reviewed.",
  "primary_amato_source": null,
  "curators": [],
  "provenance": {
    "auto": true,
    "engine": "anthropic/claude-opus-4.8",
    "question": "SQ-LIP-000013",
    "source": "library",
    "ingested": "2026-05-31"
  },
  "created": "2026-05-31",
  "updated": "2026-05-31",
  "license": "CC-BY-4.0",
  "history": [
    {
      "date": "2026-05-31",
      "event": "created"
    }
  ],
  "answers_questions": [
    {
      "id": "SQ-LIP-000013",
      "role": "supporting",
      "question": "Is liposuction effective and safe for lipedema?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000013.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000158.html"
}