{
  "id": "SCR-LIP-000266",
  "statement": "This review estimates lipedema affects approximately 1 in 9 adult women, occurs almost exclusively in women with bilateral symmetric limb adiposity sparing the feet, and notes 15-17% of patients treated for lymphedema have concomitant lipedema.",
  "statement_pt": "Esta revisão estima que o lipedema afeta aproximadamente 1 em cada 9 mulheres adultas, ocorre quase exclusivamente em mulheres com adiposidade bilateral e simétrica das extremidades poupando os pés, e observa que 15-17% das pacientes tratadas para linfedema têm lipedema concomitante.",
  "claim_type": "clinical_association",
  "context": {
    "population": "—",
    "condition": "lipedema",
    "exposure": "—",
    "comparator": "—",
    "outcome": "—",
    "scope": "auto-ingested from Layer 1 surveillance"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "very_low",
  "evidence": [
    {
      "ref": "DOI:10.1097/gox.0000000000001043",
      "stance": "supporting",
      "study_design": "review",
      "n": null,
      "risk_of_bias": "unknown",
      "grade": "very_low",
      "year": 2016,
      "amato_authored": false,
      "note": "Narrative review directly addressing prevalence and affected population, citing an estimate of ~1 in 9 adult women and near-exclusive occurrence in women; estimate is not derived from a primary epidemiological study, hence low confidence."
    }
  ],
  "relations": [],
  "gaps": "Auto-ingested single source; not yet human-reviewed.",
  "primary_amato_source": null,
  "curators": [],
  "provenance": {
    "auto": true,
    "engine": "anthropic/claude-opus-4.8",
    "question": "SQ-LIP-000002",
    "source": "library",
    "ingested": "2026-05-31"
  },
  "created": "2026-05-31",
  "updated": "2026-05-31",
  "history": [
    {
      "date": "2026-05-31",
      "event": "created",
      "detail": "auto-ingested for SQ-LIP-000002"
    }
  ],
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000002",
      "role": "supporting",
      "question": "How common is lipedema, and who does it affect?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000002.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000266.html"
}