{
  "id": "SCR-LIP-000267",
  "statement": "In a Swedish national survey of women with lipedema, 69% reported symptom onset before age 30 but the most frequent age at diagnosis was 50-59 years (34.9%), with the most common subtype being combined type 3+4 (buttocks-ankles plus arms) in 58.7% of participants.",
  "statement_pt": "Em uma pesquisa nacional sueca com mulheres com lipedema, 69% relataram início dos sintomas antes dos 30 anos, mas a idade mais frequente de diagnóstico foi 50-59 anos (34,9%), sendo o subtipo mais comum a combinação tipo 3+4 (nádegas-tornozelos mais braços) em 58,7% das participantes.",
  "claim_type": "clinical_association",
  "context": {
    "population": "—",
    "condition": "lipedema",
    "exposure": "—",
    "comparator": "—",
    "outcome": "—",
    "scope": "auto-ingested from Layer 1 surveillance"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1186/s12905-022-02022-3",
      "stance": "context",
      "study_design": "cross_sectional",
      "n": null,
      "risk_of_bias": "unknown",
      "grade": "low",
      "year": 2022,
      "amato_authored": false,
      "note": "The article describes a female-only lipedema population, including age of onset (often <30 years), age at diagnosis, comorbidities, and subtype distribution, providing demographic context relevant to who lipedema affects, though it does not"
    }
  ],
  "relations": [],
  "gaps": "Auto-ingested single source; not yet human-reviewed.",
  "primary_amato_source": null,
  "curators": [],
  "provenance": {
    "auto": true,
    "engine": "anthropic/claude-opus-4.8",
    "question": "SQ-LIP-000002",
    "source": "library",
    "ingested": "2026-05-31"
  },
  "created": "2026-05-31",
  "updated": "2026-05-31",
  "history": [
    {
      "date": "2026-05-31",
      "event": "created",
      "detail": "auto-ingested for SQ-LIP-000002"
    }
  ],
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000002",
      "role": "context",
      "question": "How common is lipedema, and who does it affect?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000002.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000267.html"
}