{
  "id": "SCR-LIP-000275",
  "statement": "Using a previously validated online screening questionnaire (cutoff ≥12 points, AUC 0.8615, specificity 0.88, sensitivity 0.46, PPV 0.767), a population-representative study estimated lipedema prevalence at 12.3% among Brazilian women aged 18-69, corresponding to roughly 8.8 million women with suggestive symptoms.",
  "statement_pt": "Utilizando um questionário de rastreamento online previamente validado (ponto de corte ≥12 pontos, AUC 0,8615, especificidade 0,88, sensibilidade 0,46, VPP 0,767), um estudo de amostra representativa estimou a prevalência de lipedema em 12,3% entre mulheres brasileiras de 18-69 anos, correspondendo a cerca de 8,8 milhões de mulheres com sintomas sugestivos.",
  "claim_type": "clinical_association",
  "context": {
    "population": "—",
    "condition": "lipedema",
    "exposure": "—",
    "comparator": "—",
    "outcome": "—",
    "scope": "auto-ingested from Layer 1 surveillance"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1590/1677-5449.202101981",
      "stance": "supporting",
      "study_design": "cross_sectional",
      "n": null,
      "risk_of_bias": "unknown",
      "grade": "low",
      "year": 2022,
      "amato_authored": false,
      "note": "The article applies a validated screening tool to estimate high lipedema prevalence in a large population, directly demonstrating that screening instruments can identify suspected lipedema cases and supporting the notion of substantial undi"
    }
  ],
  "relations": [],
  "gaps": "Auto-ingested single source; not yet human-reviewed.",
  "primary_amato_source": null,
  "curators": [],
  "provenance": {
    "auto": true,
    "engine": "anthropic/claude-opus-4.8",
    "question": "SQ-LIP-000004",
    "source": "library",
    "ingested": "2026-05-31"
  },
  "created": "2026-05-31",
  "updated": "2026-05-31",
  "history": [
    {
      "date": "2026-05-31",
      "event": "created",
      "detail": "auto-ingested for SQ-LIP-000004"
    }
  ],
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000004",
      "role": "supporting",
      "question": "Is lipedema underdiagnosed, and can screening tools help identify it?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000004.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000275.html"
}