{
  "id": "SCR-LIP-000291",
  "statement": "In a comparative study, fibromyalgia prevalence was 10% in lipedema patients (versus 28% in Dercum's disease, P=0.0003) and migraines were reported in 7% of lipedema patients (versus 21% in Dercum's, P=0.005), with a mean pain score of 4±2.5 on a 0–10 scale among lipedema patients.",
  "statement_pt": "Em um estudo comparativo, a prevalência de fibromialgia foi de 10% nos pacientes com lipedema (versus 28% na Doença de Dercum, P=0,0003) e enxaquecas foram relatadas em 7% dos pacientes com lipedema (versus 21% na Dercum, P=0,005), com escore médio de dor de 4±2,5 em escala de 0–10 entre os pacientes com lipedema.",
  "claim_type": "clinical_association",
  "context": {
    "population": "—",
    "condition": "lipedema",
    "exposure": "—",
    "comparator": "—",
    "outcome": "—",
    "scope": "auto-ingested from Layer 1 surveillance"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1038/ijo.2016.205",
      "stance": "supporting",
      "study_design": "cross_sectional",
      "n": null,
      "risk_of_bias": "unknown",
      "grade": "low",
      "year": 2017,
      "amato_authored": false,
      "note": "The article documents fibromyalgia, migraines, and pain scores as comorbidities in lipedema patients, providing direct prevalence data bearing on the question. However, prevalences are crude (unadjusted) and the primary focus is differentia"
    }
  ],
  "relations": [],
  "gaps": "Auto-ingested single source; not yet human-reviewed.",
  "primary_amato_source": null,
  "curators": [],
  "provenance": {
    "auto": true,
    "engine": "anthropic/claude-opus-4.8",
    "question": "SQ-LIP-000008",
    "source": "library",
    "ingested": "2026-05-31"
  },
  "created": "2026-05-31",
  "updated": "2026-05-31",
  "history": [
    {
      "date": "2026-05-31",
      "event": "created",
      "detail": "auto-ingested for SQ-LIP-000008"
    }
  ],
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000008",
      "role": "supporting",
      "question": "Is lipedema associated with fibromyalgia and other chronic-pain conditions?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000008.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000291.html"
}