{
  "id": "SCR-LIP-000294",
  "statement": "In a retrospective cohort of lipedema patients undergoing multistage liposuction, 22.6% had a prior migraine diagnosis, of whom 66.7% reported reduced intensity and/or frequency of attacks postoperatively (p<0.0001).",
  "statement_pt": "Em uma coorte retrospectiva de pacientes com lipedema submetidas a lipoaspiração multistage, 22,6% tinham diagnóstico prévio de migrânea, das quais 66,7% relataram redução na intensidade e/ou frequência das crises após a cirurgia (p<0,0001).",
  "claim_type": "clinical_association",
  "context": {
    "population": "—",
    "condition": "lipedema",
    "exposure": "—",
    "comparator": "—",
    "outcome": "—",
    "scope": "auto-ingested from Layer 1 surveillance"
  },
  "knowledge_state": "emerging",
  "evidence_confidence": "low",
  "evidence": [
    {
      "ref": "DOI:10.1111/dth.14534",
      "stance": "context",
      "study_design": "case_series",
      "n": null,
      "risk_of_bias": "unknown",
      "grade": "low",
      "year": 2022,
      "amato_authored": false,
      "note": "The article reports migraine prevalence (22.6%) among lipedema patients and pain-related VAS symptoms, providing contextual data on co-occurring pain conditions, but it does not assess fibromyalgia nor test an adjusted association between l"
    }
  ],
  "relations": [],
  "gaps": "Auto-ingested single source; not yet human-reviewed.",
  "primary_amato_source": null,
  "curators": [],
  "provenance": {
    "auto": true,
    "engine": "anthropic/claude-opus-4.8",
    "question": "SQ-LIP-000008",
    "source": "library",
    "ingested": "2026-05-31"
  },
  "created": "2026-05-31",
  "updated": "2026-05-31",
  "history": [
    {
      "date": "2026-05-31",
      "event": "created",
      "detail": "auto-ingested for SQ-LIP-000008"
    }
  ],
  "license": "CC-BY-4.0",
  "answers_questions": [
    {
      "id": "SQ-LIP-000008",
      "role": "context",
      "question": "Is lipedema associated with fibromyalgia and other chronic-pain conditions?",
      "url": "https://scientificclaims.org/q/SQ-LIP-000008.html"
    }
  ],
  "url": "https://scientificclaims.org/c/SCR-LIP-000294.html"
}