{
  "id": "SQ-LIP-000007",
  "question": "Is lipedema associated with thyroid disease?",
  "question_pt": "O lipedema está associado a doença da tireoide?",
  "knowledge_state": "emerging",
  "tags": [
    "Comorbidities"
  ],
  "keywords": [
    "thyroid",
    "hypothyroidism",
    "autoimmune",
    "tireoide",
    "hipotireoidismo",
    "autoimune"
  ],
  "current_answer": "One cross-sectional cohort reported thyroid disorders more often in lipedema than in lymphedema patients (24.4% vs 14.9%). The evidence is limited to a single cohort without adjustment, and the thyroid condition is not specified as autoimmune.",
  "current_answer_pt": "Uma coorte transversal relatou distúrbios tireoidianos com mais frequência no lipedema do que em pacientes com linfedema (24,4% vs 14,9%). A evidência limita-se a uma única coorte sem ajuste, e a condição tireoidiana não é especificada como autoimune.",
  "major_uncertainty": "Single cohort, no age/BMI adjustment, thyroid disorder not characterized.",
  "version": "1.0",
  "updated": "2026-05-30",
  "evidence_direction": {
    "supporting": 1,
    "contradicting": 0,
    "other": 0
  },
  "knowledge_freshness": {
    "pct": 100,
    "sources": 1,
    "newest": 2025,
    "oldest": 2025,
    "label": "current evidence base"
  },
  "claims": [
    {
      "id": "SCR-LIP-000020",
      "role": "supporting",
      "statement": "Thyroid disorders may be more frequent in lipedema than in lymphedema, with a cross-sectional cohort reporting thyroid disease in 24.4% of lipedema vs 14.89% of lymphedema patients."
    }
  ],
  "references": [
    "DOI:10.3390/jcm14207195"
  ],
  "cite": "Scientific Claim Registry. Is lipedema associated with thyroid disease?. SQ-LIP-000007 v1.0; 2026-05-30. https://scientificclaims.org/q/SQ-LIP-000007/v1.0.html",
  "versions": [
    {
      "version": "1.0",
      "date": "2026-05-30",
      "url": "https://scientificclaims.org/q/SQ-LIP-000007/v1.0.html"
    }
  ],
  "url": "https://scientificclaims.org/q/SQ-LIP-000007.html",
  "url_pt": "https://scientificclaims.org/pt/q/SQ-LIP-000007.html",
  "version_url": "https://scientificclaims.org/q/SQ-LIP-000007/v1.0.html",
  "license": "CC-BY-4.0",
  "disclaimer": "Evidence-bounded summary; not medical advice."
}