The change layer of science

Not a database of papers. A versioned memory of how scientific answers evolve.

The object is a scientific question. Underneath it sit the claims and their evidence. From those, an AI compiles a cautious, evidence-bounded answera rendering of the literature, not a verdict — and every time the evidence shifts, that answer gets a new, citable version. SCR registers; it does not arbitrate the truth.

SQ-LIP-000012● live question

Do hormones and heredity influence the onset of lipedema?

Answer · v1.10 — a synthesis, not a verdict Probably both — though the evidence remains predominantly low-to-moderate quality.

Knowledge state · ProbableFirst described · 1934Answer version · v1.10
How the answer evolved
  1. v1.1 — formalized the hormonal hypotheses (onset at puberty, pregnancy, menopause)
  2. v1.3 — added genetic evidence: multiple GWAS, including UK Biobank loci
  3. v1.10 — current synthesis: hormones and heredity, graded Probable
Open this question · see every version →

425 of 433 evidence sources independently AI-verified · 1 disputed

Papers have DOIs. Researchers have ORCIDs. Clinical trials have registration numbers. SCR gives scientific questions and claims the same: persistent identifiers, evidence provenance, version history, supporting and contradictory evidence, and a machine-readable structure that LLMs can read.

The goal is not to determine truth, but to make the evolution of scientific knowledge traceable. Pilot domain: lipedema. Operated by the BIO (Biological Intelligence Observatory) research method. Open access · CC BY 4.0 · Founder: Dr. Alexandre C. M. Amato. Not medical advice.