SCR-LIP-000034 · Claim · machine-readable JSON →

Ultrasound-assisted liposuction may reduce postoperative seroma risk in lipedema surgery (0 seromas among ultrasound-assisted cases vs 18.4% otherwise), although this finding is hypothesis-generating only.

Speculative therapeutic Evidence certainty: very low (GRADE)

Evidence over time

DOI:10.1007/s00266-026-05774-7 — supporting · cohort · n=93 · 2026 · risk of bias: high
0/14 vs 17/76 (p=0.065 NS); zero-event, author-labeled hypothesis-generating

Populationwomen undergoing liposuction for lipedema

Conditionlipedema

Exposureultrasound-assisted liposuction

Comparatornon-ultrasound liposuction

Outcomepostoperative seroma

Scopepotential protective effect of an adjunct

Small subgroup (n=14); zero-event problem; not statistically significant; needs controlled validation.