SCR-LIP-000040 · Claim · machine-readable JSON →
There is no scientific evidence supporting gestrinone for lipedema: a PRISMA systematic review identified zero clinical trials, observational studies or case reports evaluating it, particularly as subcutaneous implants.
Evidence over time
Evidence (1)
- DOI:10.7759/cureus.97213 — contradicting · systematic review · 2025 · risk of bias: low
zero eligible studies; SBEM and Brazilian Lipedema Association oppose use
Context (PECO)
Answers these questions
- Is gestrinone an effective treatment for lipedema? contradicting
Gaps & caveats
Absence of evidence (no studies) rather than demonstrated lack of effect; implant pharmacokinetics/safety never studied.