SCR-LIP-000142 · Claim · machine-readable JSON →

Lipedema is a chronic disorder presenting almost exclusively in women, typically beginning during periods of hormonal change such as puberty, childbirth, or menopause, with an autosomal dominant inheritance pattern showing female preference and reported prevalence in lymphology clinics of 6.5–18.8%.

Emerging clinical association Evidence certainty: low (GRADE)

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Lipedema: friend and foe — Torre et al. (2018) — supporting · review · 2018
The article (review plus chart review of 46 women) explicitly addresses who lipedema affects (women, onset at hormonal life stages, autosomal dominant inheritance with female preference) and cites prevalence figures from clinical settings (

Conditionlipedema

Scopeauto-ingested from Layer 1 surveillance

Auto-ingested single source; not yet human-reviewed.