SCR-LIP-000156 · Claim · machine-readable JSON →
A case report of idiopathic lipedema in a 62-year-old male—only the third such male case reported worldwide—notes that two of the three known male cases had associated hormonal alterations (alcoholic cirrhosis; type 1 diabetes plus alcohol abuse), and the near-exclusive female predominance is cited as suggesting a hormonal role in pathogenesis.
Created: 2026-05-31 · Last updated: 2026-05-31
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- DOI:10.3205/iprs000161 — supporting · case report · 2021
Single male case report that explicitly raises a hormonal hypothesis based on female predominance and observed endocrine comorbidities, but provides no direct test of hormonal or hereditary causation and addresses heredity only minimally.
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Auto-ingested single source; not yet human-reviewed.
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- 2026-05-31 — created