SCR-LIP-000205 · Claim · machine-readable JSON →

In this systematic review, non-contrast CT showed 95% sensitivity and 100% specificity for diagnosing lipedema (Monnin-Delhom), and imaging plus clinical signs (sparing of the foot dorsum, negative Stemmer sign) differentiate lipedema from lymphedema.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• Lipedema: an overview of its clinical manifestations, diagnosis and treatment of the disproportional fatty deposition syndrome – systematic review — Forner‐Cordero et al. (2012) — supporting · review · 2012
  The review summarizes imaging diagnostic performance (CT sensitivity/specificity) and differential diagnostic criteria distinguishing lipedema from lymphedema, directly addressing whether imaging can differentiate these conditions, though i

Context (PECO)

Answers these questions

• Can MRI, lymphoscintigraphy, or DXA differentiate lipedema from lymphedema and other fat distributions? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000023

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