SCR-LIP-000208 · Claim · machine-readable JSON →

In patients with lipedema (mean baseline BMI 48.5), bariatric surgery (sleeve gastrectomy or RYGB) reduced adjusted thigh volume by 33.4% at first follow-up, comparable to the 37.0% reduction in lymphedema controls (p>0.999), with greater reduction in those with BMI ≥50 (44.4% vs 33.2% for BMI 35-<50) and reduction correlating with excess BMI loss.

Emerging clinical association Evidence certainty: moderate (GRADE)

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

2020Leg Volume in Patients with Lipoedema following Bariatric Surgery — Fink et al. (2020) · supporting

Evidence (1)

Context (PECO)

Conditionlipedema
Scopeauto-ingested from Layer 1 surveillance

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Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

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