SCR-LIP-000269 · Claim · machine-readable JSON →
Using 15 MHz cutaneous ultrasonography with computer-assisted (ImageJ) measurement of dermal echogenicity, lipedema was characterized by increased subcutaneous thickness and subcutaneous hypoechogenicity throughout the limb (subcutaneous echogenicity at calf ~60 vs 79 in lymphedema, p=0.005) and a preserved dermal:subcutaneous echogenicity ratio, distinguishing it from lymphedema which showed predominantly distal dermal thickening and dermal hypoechogenicity.
Created: 2026-05-31 · Last updated: 2026-05-31
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- DOI:10.1089/lrb.2017.0090 — supporting · cross sectional · 2019
Comparative ultrasound study directly addressing whether cutaneous ultrasonography can characterize/differentiate lipedema, reporting specific quantitative sonographic features; limitations include age imbalance between groups noted by auth
Context (PECO)
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Auto-ingested single source; not yet human-reviewed.
Change log
- 2026-05-31 — created · auto-ingested for SQ-LIP-000003