SCR-LIP-000274 · Claim · machine-readable JSON →
High-resolution duplex sonography (11-12 MHz) measuring subcutis+cutis thickness 8 cm above the medial malleolus distinguished lipedema (~16 mm) from non-lipedema (11±2.8 mm) and at the medial knee (25.5 mm vs 14.7±5 mm), with proposed severity grading (12-15 mm mild, 15-20 mm moderate, >20 mm distinct, >30 mm marked) and a homogeneously hyperechogenic 'snow storm' subcutis without echo-free clefts differentiating lipedema from lymphedema.
Created: 2026-05-31 · Last updated: 2026-05-31
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- DOI:10.1055/s-0037-1621766 — supporting · cross sectional · 2011
Cross-sectional prevalence study (n=62) explicitly validating quantitative ultrasonographic criteria for diagnosing and grading lipedema and differentiating it from lymphedema, directly supporting that ultrasound can diagnose/classify liped
Context (PECO)
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Gaps & caveats
Auto-ingested single source; not yet human-reviewed.
Change log
- 2026-05-31 — created · auto-ingested for SQ-LIP-000003