SCR-LIP-000292 · Claim · machine-readable JSON →

In a Swiss cohort of 381 lipedema patients, pain was reported by 87.9% (high pain BPI≥7 in 14.2%) and high fatigue (FSS≥4) in 56.1%, but rheumatic comorbidities and chronic-pain-specific conditions such as fibromyalgia were not separately quantified, and joint hypermobility (Beighton≥5) was present in only 4.2%.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1371/journal.pone.0319099 — context · cross sectional · 2025
  The article documents high prevalence of pain and fatigue and includes a rheumatic comorbidity category, but does not specifically report fibromyalgia or other defined chronic-pain conditions, so it provides only contextual symptom data rat

Context (PECO)

Answers these questions

• Is lipedema associated with fibromyalgia and other chronic-pain conditions? context

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000008

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