SCR-LIP-000337 · Claim · machine-readable JSON →

This systematic review describes lipedema staging (Stage III with peau d'orange) and a lipo-lymphedema type (Schingale type V), notes a negative Stemmer sign and foot sparing distinguishing it from lymphedema, and recommends early diagnosis and treatment to prevent functional and cosmetic complications.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1111/j.1758-8111.2012.00045.x — supporting · review · 2012
  The review references lipo-lymphedema as an advanced type/stage and warns of functional complications, providing descriptive evidence consistent with progression to lymphedema and disability, though without quantitative progression data or

Context (PECO)

Answers these questions

• Does lipedema progress to lymphedema and cause functional disability? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000017

← All claims