SCR-LIP-000349 · Claim · machine-readable JSON →

In a survey of lipedema patients comparing self-reported stages, more advanced stage (3-4) was associated with higher rates of depression (48.3% vs 34.8%, p<0.001), social isolation (staying home 64.3% vs 44.4%), life dissatisfaction (35.7% vs 22.0%), and loss of mobility, while psychological burden such as inferiority complex (72.8%) and constantly thinking about lipedema (73.4%) was high across all stages.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1007/s11136-022-03216-w — supporting · cross sectional · 2023
  Large cross-sectional survey directly reports depression, anxiety-related symptoms (fearfulness), social isolation, and life dissatisfaction in lipedema patients, with worse outcomes at advanced stages; findings are self-reported and unadju

Context (PECO)

Answers these questions

• How does lipedema affect quality of life, depression, and anxiety in affected patients? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000020

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