SCR-LIP-000354 · Claim · machine-readable JSON →

In a national Swedish survey of women with lipedema, RAND-36 scores were 25-35 points below the age-matched general female population across all subscales (largest gap in physical role functioning, ~43 points lower in ages 60-79; smallest in emotional well-being, ~10 points), with worse physical and social functioning at higher lipedema stages and a self-reported depression prevalence of 13.5%.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1186/s12905-022-02022-3 — supporting · cross sectional · 2022
  Cross-sectional national survey directly measuring health-related quality of life (RAND-36, including emotional well-being subscale) and reporting depression prevalence, with comparison to a general population, directly addressing the quest

Context (PECO)

Answers these questions

• How does lipedema affect quality of life, depression, and anxiety in affected patients? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000020

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