SCR-LIP-000366 · Claim · machine-readable JSON →
In a Swiss cohort of 381 lipedema patients classified by type (I-V) and stage (1-4), advanced stage correlated with age and BMI, but a Stemmer sign was positive in only 4.0% and validated questionnaire scores (HADS, BPI, FSS, SF-36) did not differ significantly between stages (p>0.5), revealing a dissociation between morphological stage and symptom burden.
Claim at a glance
- Type
- clinical association
- Knowledge state
- Emerging
- Evidence certainty
- moderate (GRADE)
- Evidence
- 1 source(s)
- Answers
- 1 question(s)
- Dates
- 2026-05-31 → 2026-05-31
Structured evidence, machine-compiled — not a verdict.
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- Clinical characteristics, comorbidities, and correlation with advanced lipedema stages: A retrospective study from a Swiss referral centre — Luta et al. (2025) ✓ verified — contextual · cohort · 2025 · reading confidence: high
The article applies the standard type (I-V) and stage (1-4) classification systems and reports their clinical correlates, including a dissociation between morphological stage and symptoms and the diagnostic relevance of negative Stemmer sig
Context (PECO)
Answers these questions
Gaps & caveats
Auto-ingested single source; not yet human-reviewed.
Change log
- 2026-05-31 — created · auto-ingested for SQ-LIP-000022