SCR-LIP-000370 · Claim · machine-readable JSON →

A retrospective study of 34 women with lipedema using high-frequency B-mode ultrasound (10-15 MHz) across three platforms proposes a new qualitative Lipedema Dermal and Hypodermal Classification (LDHC) with four stages distinguishing preserved architecture (LDHC 1), bulging architecture (LDHC 2), inflammatory phenotype with hyperechoic nodules (LDHC 3), and fibrotic 'marbled' phenotype with septal verticalization (LDHC 4), intended to complement existing anatomical and functional classifications.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.4236/jbise.2025.184008 — refines · cross sectional · 2025
  The article proposes a new qualitative ultrasonographic classification system for lipedema, directly addressing classification/grading approaches in the question, and reports an initial assessment of cross-platform reproducibility, refining

Context (PECO)

Answers these questions

• What clinical criteria and stage/type classification systems are used to diagnose and grade lipedema, and how reliable are they? refines

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000022

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