SCR-LIP-000371 · Claim · machine-readable JSON →

This review describes lipedema clinical presentation using a classification of 5 types by anatomical fat distribution (I: hip/buttocks; II: hip to knee; III: hip to ankle; IV: also arms in ~80% of women; V: calf only) and 4 stages (I: smooth skin with enlarged hypodermis; II: palpable nodules with peau d'orange; III: deforming fat masses with folds; IV: lipolymphedema with positive Stemmer sign), and notes that only 46.2% of surveyed vascular consultants could recognize the disease.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1002/oby.22597 — context · review · 2019
  The narrative review explicitly presents the type (5-type distribution) and stage (4-stage) classification systems used to diagnose and grade lipedema, directly addressing the question's criteria component, and notes low clinical recognitio

Context (PECO)

Answers these questions

• What clinical criteria and stage/type classification systems are used to diagnose and grade lipedema, and how reliable are they? context

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000022

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