SCR-LIP-000372 · Claim · machine-readable JSON →

In a cross-sectional study of 115 Saudi patients with lower-limb edema, clinical diagnosis of lipedema used a structured assessment including signs (cuff/collar sign, Stemmer sign, telangiectasias, non-pitting orthostatic edema), severity grading 1-4 and anatomical type classification 1-5; clinical criteria confirmed lipedema in 71% (82/115), grade 2 was most common (31%), type 3 (hip-to-ankle) predominant (47%), and the cuff/collar sign correlated with advanced stages (80% of those with the sign were ≥grade 2).

Claim at a glance

Structured evidence, machine-compiled — not a verdict.

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Characteristics and Clinical Features of Patients with Lipedema in Saudi Arabia: A Cross-sectional Comprehensive Assessment — Alosaimi et al. (2024) ✓ verified — consistent · cross sectional · 2024 · reading confidence: high
“Sinal de colar correlacionou-se com estágios avançados (80% dos com sinal de colar eram ≥G2); ausência do sinal correlacionou com G1 ou nenhum (68%).”
The study explicitly applies clinical diagnostic criteria, a 1-4 grading system, and a 1-5 type classification, reporting their distribution and a correlation between the collar sign and disease stage, directly bearing on the question of cl

PopulationSaudi patients with lower-limb edema (n=115)

Conditionlipedema

Exposurestructured clinical lipedema assessment with sign/grade/type criteria

Outcomelipedema diagnosis, grade, type, and sign-stage correlation

Scopeauto-ingested from Layer 1 surveillance

Auto-ingested single source; not yet human-reviewed.