SCR-LIP-000374 · Claim · machine-readable JSON →

Using ICG lymphography in 45 women with lipedema classified by different types and stages, lymphatic function (dye transit speed) correlated with symptom duration (T25' vs duration r=-0.469, p=0.037) rather than with lipedema stage or fat accumulation, and a linear lymphatic pattern was found in 100% of patients with no major anatomical abnormalities.

Claim at a glance

Structured evidence, machine-compiled — not a verdict.

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Indocyanine green lymphography as novel tool to assess lymphatics in patients with lipedema — Buso et al. (2021) ✓ verified — contextual · cross sectional · 2021 · reading confidence: high
“O funcionamento linfático em pacientes com lipedema correlaciona-se com a duração dos sintomas, sugerindo que a velocidade do ICG nos linfáticos superficiais depende principalmente do tempo de evolução da doença, e não do grau de acúmulo de gordura ou do estadiamento. Não foram encontradas alteraçõe”
The article applies lipedema type/stage classification to its cohort but focuses on ICG lymphographic assessment of lymphatic function, not on the diagnostic criteria or reliability of classification systems themselves; it notes that lympha

Populationwomen with lipedema, various types and stages (n=45)

Conditionlipedema

ExposureICG lymphography assessment of lymphatic function

Comparatorlipedema stage and fat accumulation measures

Outcomedye transit speed correlated with symptom duration

Scopeauto-ingested from Layer 1 surveillance

Auto-ingested single source; not yet human-reviewed.