SCR-LIP-000391 · Claim · machine-readable JSON →
In a 7-week eucaloric ketogenic (LCHF) diet pilot study of women with lipedema, weight loss of −4.6±0.7 kg was accompanied by reduced waist (−4.3 cm) and hip (−2.2 cm) circumferences but NO significant thigh reduction (p=0.20), and pain reduction at week 7 did not correlate with weight loss (r=0.283, p=0.46), indicating lipedematous fat resists weight-loss-driven volume change and symptom benefits appear independent of weight loss.
Created: 2026-05-31 · Last updated: 2026-05-31
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- DOI:10.1002/osp4.580 — refines · case series · 2021
Small uncontrolled pilot study addressing whether weight loss (via ketogenic diet) alters lipedema fat volume and symptoms; finds regional thigh fat resistant to weight loss and pain improvement dissociated from weight loss, refining the af
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Auto-ingested single source; not yet human-reviewed.
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- 2026-05-31 — created · auto-ingested for SQ-LIP-000024