SCR-LIP-000015 · Claim · machine-readable JSON →
Women meeting lipedema screening criteria have a higher prevalence of positive ADHD self-report (ASRS-18) than women without lipedema (76.9% vs 54%; RR 1.424).
Claim at a glance
- Type
- clinical association
- Knowledge state
- Emerging
- Evidence certainty
- low (GRADE)
- Evidence
- 3 source(s) · by Amato
- Answers
- 1 question(s)
- Dates
- 2026-05-30 → 2026-06-12
Structured evidence, machine-compiled — not a verdict.
Evidence over time
Evidence (3)
- The Association Between Lipedema and Attention-Deficit/Hyperactivity Disorder — Amato et al. (2023) ✓ verified — consistent · cross sectional · n=354 · 2023 · risk of bias: moderate · reading confidence: high
“Risco relativo de TDAH em mulheres com lipedema: RR=1,424 (IC 95%: 1,2218–1,6598; p<0,0001)”
RR 1.424 (95%CI 1.22-1.66), p<0.0001; self-report screening - Lipedema as a Syndrome of Adipose Mast Cell Activation and Type 2 Immune Orchestration: A Testable Neuroimmune Framework — Amato (2026) ✓ verified — consistent · review · 2026 · reading confidence: moderate
“clínicos (FM 35–40%, ADHD 1,42 RR, hEDS 44%, joelho 58,1%)”
The article discusses the comorbidity of lipedema with ADHD, providing evidence of a potential association. - The Evolutionary Theory of Lipedema: A Perspective on Energy Storage and Chronic Inflammation — Amato (2025) ✓ verified — consistent · review · 2025 · reading confidence: high
The article discusses the relationship between lipedema and ADHD, indicating a potential association that warrants further investigation.
Context (PECO)
Answers these questions
- Is lipedema associated with ADHD? consistent
Gaps & caveats
Self-reported screening, convenience sampling, no confounder adjustment, single study.
Change log
- 2026-05-30 — created
- 2026-05-30 — corroborated_by_layer1 · DOI:10.20944/preprints202605.1114.v1
- 2026-05-30 — corroborated_by_layer1 · DOI:10.7759/cureus.88809
- 2026-06-12 — disputed evidence reviewed · Human review: synthesis — this source supports the claim's direction; the specific(s) it lacks are present in a sibling source (per-claim integrity clean). Accepted.