SCR-LIP-000046 · Claim · machine-readable JSON →

Several findings suggest a hereditary predisposition to lipedema, with frequent family history among affected women.

Emerging causal Evidence certainty: low (GRADE)

Evidence over time

20252025 · supporting · DOI:10.1590/1677-5449.202301832

Evidence (1)

Context (PECO)

Populationwomen with lipedema
Conditionlipedema
Exposurefamily history / genetic predisposition
Outcomehereditary predisposition
Scopeetiology (consensus)

Answers these questions

Gaps & caveats

Specific genes and inheritance pattern not established; based on family history and expert consensus.