SCR-LIP-000080 · Claim · machine-readable JSON →

In a Swiss referral centre cohort of 381 women with lipedema (mean age 41.9 years), 49.9% reported a family history, 62.2% reported symptom onset during adolescence, and 92.1% had comorbidities, with pain affecting 87.9% and significantly reduced quality of life in the majority.

Claim at a glance
Type
clinical association
Knowledge state
Emerging
Evidence certainty
moderate (GRADE)
Evidence
1 source(s)
Dates
2026-05-31 → 2026-05-31

Structured evidence, machine-compiled — not a verdict.

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-sonnet-4.6 · 2026-05-31

Evidence over time

2025Clinical characteristics, comorbidities, and correlation with advanced lipedema stages: A retrospective study from a Swiss referral centre — Luta et al. (2025) · contextual

Evidence (1)

Context (PECO)

Populationwomen with lipedema at Swiss referral centre (n=381)
Conditionlipedema
Exposureclinical and demographic characteristics assessment
Outcomefamily history, onset age, comorbidities, pain, QoL
Scopeauto-ingested from Layer 1 surveillance

Answers these questions

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log