SCR-LIP-000080 · Claim · machine-readable JSON →

In a Swiss referral centre cohort of 381 women with lipedema (mean age 41.9 years), 49.9% reported a family history, 62.2% reported symptom onset during adolescence, and 92.1% had comorbidities, with pain affecting 87.9% and significantly reduced quality of life in the majority.

Emerging clinical association Evidence certainty: moderate (GRADE)

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-sonnet-4.6 · 2026-05-31

Evidence over time

2025Clinical characteristics, comorbidities, and correlation with advanced lipedema stages: A retrospective study from a Swiss referral centre — Luta et al. (2025) · context

Evidence (1)

Context (PECO)

Conditionlipedema
Scopeauto-ingested from Layer 1 surveillance

Answers these questions

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.