SCR-LIP-000123 · Claim · machine-readable JSON →

Lymphoscintigraphy in 19 lipedema patients revealed pathologic lymphatic transport (TI >10) in 63.2% of lower extremities, with significantly higher transport index scores in severe (stage 3/4) versus mild/moderate (stage 1/2) lipedema (mean TI 15.1 vs 9.7, p=0.049), indicating progressive lymphatic dysfunction associated with clinical severity.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-sonnet-4.6 · 2026-05-31

Evidence over time

Evidence (1)

• Uncovering Lymphatic Transport Abnormalities in Patients with Primary Lipedema — Gould et al. (2019) — supporting · cross sectional · 2019
  This cross-sectional study directly addresses lymphatic dysfunction in lipedema and its association with clinical staging, providing objective lymphoscintigraphic evidence that lymphatic transport abnormalities worsen with lipedema severity

Context (PECO)

Answers these questions

• Does lipedema progress to lymphedema and cause functional disability? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created

← All claims