SCR-LIP-000137 · Claim · machine-readable JSON →

In a Brazilian cross-sectional screening study, hypothyroidism was common in women with lipedema (crude prevalence 19.4%) but was NOT an independent factor associated with lipedema on multivariate analysis (p=0.141) — the raw co-occurrence may reflect confounding (e.g. by obesity) rather than a true independent association.

Emerging epidemiologic Evidence certainty: low (GRADE)

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-sonnet-4.6 · 2026-05-31

Evidence over time

2022Lipedema prevalence and risk factors in Brazil — Amato et al. (2022) · refines

Evidence (1)

Context (PECO)

Conditionlipedema
Scopeauto-ingested from Layer 1 surveillance

Answers these questions

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

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