SCR-LIP-000138 · Claim · machine-readable JSON →

This systematic review reports lipedema prevalence estimates of 11% in women (Földi), 15% of patients in a lymphology clinic (Herpertz), and 18.8% of 843 patients with lower-limb enlargement, occurring almost exclusively in women, with positive family history in 16–64% of cases.

Emerging clinical association Evidence certainty: low (GRADE)

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Lipedema: an overview of its clinical manifestations, diagnosis and treatment of the disproportional fatty deposition syndrome – systematic review — Forner‐Cordero et al. (2012) — supporting · review · 2012
The review directly compiles epidemiological data on lipedema prevalence, sex distribution (almost exclusively women), and familial occurrence, directly addressing how common lipedema is and who it affects.

Conditionlipedema

Scopeauto-ingested from Layer 1 surveillance

Auto-ingested single source; not yet human-reviewed.