SCR-LIP-000138 · Claim · machine-readable JSON →

This systematic review reports lipedema prevalence estimates of 11% in women (Földi), 15% of patients in a lymphology clinic (Herpertz), and 18.8% of 843 patients with lower-limb enlargement, occurring almost exclusively in women, with positive family history in 16–64% of cases.

Claim at a glance
Type
clinical association
Knowledge state
Emerging
Evidence certainty
low (GRADE)
Evidence
1 source(s)
Dates
2026-05-31 → 2026-05-31

Structured evidence, machine-compiled — not a verdict.

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

2012Lipedema: an overview of its clinical manifestations, diagnosis and treatment of the disproportional fatty deposition syndrome – systematic review — Forner‐Cordero et al. (2012) · consistent

Evidence (1)

Context (PECO)

Populationwomen with lower-limb enlargement or lymphology patients
Conditionlipedema
Exposurelipedema diagnosis
Comparatorgeneral or clinic female population
Outcomeprevalence and family history rate
Scopeauto-ingested from Layer 1 surveillance

Answers these questions

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

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