SCR-LIP-000144 · Claim · machine-readable JSON →

In a cross-sectional study of 258 women with clinically diagnosed lipedema stratified by BMI, the prevalence of lower-limb clinical lymphedema rose from 6.1% (BMI <30) to 51.6% (BMI 30-40) to 77.8% (BMI 40-50), and subclinical systemic lymphedema from 16.3% to 48.3% to 72.2%, with a dose-response gradient by BMI.

Emerging clinical association Evidence certainty: low (GRADE)

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

2020Lipedema and the Evolution to Lymphedema With the Progression of Obesity — Pereira de Godoy et al. (2020) · context

Evidence (1)

Context (PECO)

Conditionlipedema
Scopeauto-ingested from Layer 1 surveillance

Answers these questions

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

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