SCR-LIP-000153 · Claim · machine-readable JSON →
In a survey of 209 lipedema patients, symptom onset clustered in adolescence (mean age 16±9 years, 32.5% at ages 14-18), family history was common (affected grandmothers 35.4%, mothers 29.7%, aunts 23.0%), and 30.5% of premenopausal patients had sex-hormone imbalances, consistent with hormonal and hereditary contributions to lipedema onset.
Created: 2026-05-31 · Last updated: 2026-05-31
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- New Insights on Lipedema: The Enigmatic Disease of the Peripheral Fat — Bauer et al. (2019) — supporting · cross sectional · 2019
Cross-sectional survey reporting adolescent/hormonal onset timing and high familial prevalence, supporting hormonal and hereditary influence on lipedema onset, though descriptive without adjusted analysis.
Context (PECO)
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Gaps & caveats
Auto-ingested single source; not yet human-reviewed.
Change log
- 2026-05-31 — created