SCR-LIP-000158 · Claim · machine-readable JSON →
In 191 women with lower-limb lipedema (stages 1–3), a standardized two-stage lymph-sparing VASER ultrasound-assisted liposuction protocol reduced mean total limb circumference by 6.40 cm and mean VAS symptom score from 6.04 to 3.17 (p<0.001), with 89.8% patient satisfaction and complications including seroma (5.75%), skin necrosis (2.09%), and transfusion (3.14-4.18%).
Claim at a glance
- Type
- clinical association
- Knowledge state
- Emerging
- Evidence certainty
- low (GRADE)
- Evidence
- 1 source(s)
- Answers
- 3 question(s)
- Dates
- 2026-05-31 → 2026-06-11
Structured evidence, machine-compiled — not a verdict.
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- Observational Study of Ultrasound-Assisted Liposuction for Lower Limb Lipedema on 191 Female Patients — Hersant et al. (2025) ✓ verified — consistent · case series · 2025 · reading confidence: high
Observational single-arm study of 191 patients reporting significant reductions in circumference and pain plus complication rates, directly supporting liposuction efficacy and safety for lipedema; no control group and short 6-month follow-u
Context (PECO)
Answers these questions
- Is liposuction effective and safe for lipedema? consistent
- Does liposuction reduce pain in lipedema? consistent
- Does liposuction reduce limb volume in lipedema? consistent
Gaps & caveats
Auto-ingested single source; not yet human-reviewed.
Change log
- 2026-05-31 — created
- 2026-06-10 — statement revised · R-AI-14 fabrication review: 'stage 3'→'type 3' (source says lower-limb lipedema TYPE 3 — distribution axis, not severity stage).
- 2026-06-11 — statement revised · R-AI-14 fabrication review: cohort is 'stages 1–3' per the source's English METHODS (191 patients); fixes both the original 'stage 3' and the interim 'type 3' (the PT objective's 'tipo 3' is a source translation inconsistency).