SCR-LIP-000188 · Claim · machine-readable JSON →

A simplified 9-item self-applied screening questionnaire (derived from the validated QuASiL) based on clinical diagnostic criteria (post-pubertal women, bilateral symmetric fat deposit below the hip sparing feet, negative Stemmer and Godet signs, pain on palpation, spontaneous bruising) achieved diagnostic discrimination of AUC=0.912 for an individual 7-question predictive model and AUC=0.8615 for a total-score model against expert clinical diagnosis in 109 women (59 with lipedema, 50 without), with the item 'feeling something wrong in the legs' being most discriminative (OR=4.328).

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• Criação de questionário e modelo de rastreamento de lipedema — Amato et al. (2020) — refines · cross sectional · 2020
  The article develops and validates a screening tool grounded in standard clinical diagnostic criteria for lipedema and reports diagnostic accuracy (AUC) against expert clinical reference, directly bearing on diagnostic criteria and their re

Context (PECO)

Answers these questions

• What clinical criteria and stage/type classification systems are used to diagnose and grade lipedema, and how reliable are they? refines

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000022

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