SCR-LIP-000266 · Claim · machine-readable JSON →

This review estimates lipedema affects approximately 1 in 9 adult women, occurs almost exclusively in women with bilateral symmetric limb adiposity sparing the feet, and notes 15-17% of patients treated for lymphedema have concomitant lipedema.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1097/gox.0000000000001043 — supporting · review · 2016
  Narrative review directly addressing prevalence and affected population, citing an estimate of ~1 in 9 adult women and near-exclusive occurrence in women; estimate is not derived from a primary epidemiological study, hence low confidence.

Context (PECO)

Answers these questions

• How common is lipedema, and who does it affect? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000002

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