SCR-LIP-000275 · Claim · machine-readable JSON →

Using a previously validated online screening questionnaire (cutoff ≥12 points, AUC 0.8615, specificity 0.88, sensitivity 0.46, PPV 0.767), a population-representative study estimated lipedema prevalence at 12.3% among Brazilian women aged 18-69, corresponding to roughly 8.8 million women with suggestive symptoms.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1590/1677-5449.202101981 — supporting · cross sectional · 2022
  The article applies a validated screening tool to estimate high lipedema prevalence in a large population, directly demonstrating that screening instruments can identify suspected lipedema cases and supporting the notion of substantial undi

Context (PECO)

Answers these questions

• Is lipedema underdiagnosed, and can screening tools help identify it? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000004

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