SCR-LIP-000277 · Claim · machine-readable JSON →
In non-obese lipedema patients, standardized QST (DFNS protocol) revealed selective alterations in only 2 of 13 parameters at the affected lateral thigh—elevated pressure pain (PPT, AUC 0.9075) and reduced vibration detection (VDT, AUC 0.8638)—and a combined PPT+VDT z-score score was proposed as a rapid diagnostic test for lipedema.
Claim at a glance
- Type
- clinical association
- Knowledge state
- Emerging
- Evidence certainty
- low (GRADE)
- Evidence
- 1 source(s)
- Answers
- 2 question(s)
- Dates
- 2026-05-31 → 2026-05-31
Structured evidence, machine-compiled — not a verdict.
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- Non-obese lipedema patients show a distinctly altered Quantitative Sensory Testing profile with high diagnostic potential — Dinnendahl et al. (2023) ✓ verified — consistent · cross sectional · 2023 · reading confidence: high
“testar se os parametros alterados podem servir de base para um teste diagnostico rapido (PVTH-score)”
Cross-sectional case-control comparison proposing a quantitative sensory testing-based diagnostic score (PVTH-score) with high discriminative accuracy, directly addressing the development of a screening/diagnostic tool for identifying liped
Context (PECO)
Answers these questions
- Is lipedema underdiagnosed, and can screening tools help identify it? consistent
- Can screening tools or questionnaires help identify lipedema cases? consistent
Gaps & caveats
Auto-ingested single source; not yet human-reviewed.
Change log
- 2026-05-31 — created · auto-ingested for SQ-LIP-000004