SCR-LIP-000283 · Claim · machine-readable JSON →

In a cohort of 83 women with clinically diagnosed lipedema, symptoms began at a mean age of 20.4 years but diagnosis occurred at a mean age of 46.5 years, indicating a mean diagnostic delay of 26.1 years, while lymphoscintigraphy showed lymphatic alterations in 47% of patients across all clinical stages.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1016/j.remn.2018.06.008 — context · cohort · 2018
  The article documents a substantial diagnostic delay (26.1 years on average), which contextually supports the notion that lipedema is underdiagnosed, but the study's primary aim concerns lymphoscintigraphic findings rather than evaluating s

Context (PECO)

Answers these questions

• Is lipedema underdiagnosed, and can screening tools help identify it? context

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000004

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