SCR-LIP-000285 · Claim · machine-readable JSON →

A systematic review reported that lipedema is poorly recognized clinically—only 46.2% of 251 Vascular Society of Great Britain and Ireland consultants recognized it (Tiwari 2006)—and that it was absent from MeSH/EMBASE and ICD-WHO as of 2012, while non-contrast CT showed 95% sensitivity and 100% specificity and the spared foot dorsum (negative Stemmer sign) helps distinguish lipedema from lymphedema.

Created: 2026-05-31 · Last updated: 2026-05-31

Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31

Evidence over time

Evidence (1)

• DOI:10.1111/j.1758-8111.2012.00045.x — supporting · review · 2012
  The review explicitly documents widespread under-recognition of lipedema (low clinician recognition rate, absence from coding systems, 'hidden epidemic') and describes diagnostic criteria and imaging tools (clinical staging, CT sensitivity/

Context (PECO)

Answers these questions

• Is lipedema underdiagnosed, and can screening tools help identify it? supporting

Gaps & caveats

Auto-ingested single source; not yet human-reviewed.

Change log

• 2026-05-31 — created · auto-ingested for SQ-LIP-000004

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