SCR-LIP-000288 · Claim · machine-readable JSON →
In a prospective cohort of 138 lipedema and 111 lymphedema patients, a CART algorithm using only three clinical variables (bruising, body disproportion, and non-swollen/spared feet) classified lipedema versus lymphedema with 100% accuracy, and the median time from symptom onset to diagnosis was markedly longer in lipedema (25.5 years vs 12.1 years for lymphedema, p<0.0001).
Created: 2026-05-31 · Last updated: 2026-05-31
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-05-31
Evidence over time
Evidence (1)
- DOI:10.23736/s0392-9590.25.05207-1 — supporting · cohort · 2025
The article reports a chronic diagnostic delay in lipedema (25.5 years to diagnosis), supporting underdiagnosis, and develops a simple 3-variable screening/classification tree to identify lipedema versus lymphedema, directly addressing both
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- 2026-05-31 — created · auto-ingested for SQ-LIP-000004