SCR-LIP-000398 · Claim · machine-readable JSON →
In 151 women, those with lipoedema (N=90) reported significantly higher LYMQOL-leg burden scores for symptoms (p=0.003), appearance (p=0.003) and mood (p=0.011), and worse LSIDS-L neurological, biobehavioral and resource scores than those with bilateral leg lymphoedema (N=61), indicating distinguishable HRQoL profiles despite similar symptoms.
Claim at a glance
- Type
- clinical association
- Knowledge state
- Emerging
- Evidence certainty
- low (GRADE)
- Evidence
- 1 source(s)
- Answers
- 1 question(s)
- Dates
- 2026-06-07 → 2026-06-07
Structured evidence, machine-compiled — not a verdict.
Auto-compiled by the Layer 1 surveillance loop; not yet human-reviewed. anthropic/claude-opus-4.8 · 2026-06-07
Evidence over time
Evidence (1)
- A retrospective cross-sectional study comparing health-related quality-of-life in females with lipoedema and bilateral leg lymphoedema. — Stellmaker R, Thompson B, Mackie H, Paramanandam VS, Sherman KA, Koelmeyer L. (2026) — refining · cross sectional · 2026
The study found lipoedema and lymphoedema differ in specific HRQoL outcomes while sharing similar symptoms, supporting a qualified distinction between the conditions but only via patient-reported outcomes, not pathophysiology.
Context (PECO)
Answers these questions
Gaps & caveats
Auto-ingested single source; not yet human-reviewed.
Change log
- 2026-06-07 — created · auto-ingested for SQ-LIP-000001