SQ-LIP-000008 · v1.0 (current) · machine-readable JSON →
Is lipedema associated with fibromyalgia and other chronic-pain conditions?
Observational studies report frequent co-occurrence: lipedema was found in about half of women meeting fibromyalgia criteria in one study, and knee pain is commonly reported by women screening positive for lipedema. Direction of the relationship is unclear and most data are self-reported or single-center.
Knowledge freshness = share of the 2 indexed evidence sources from the last 5 years (newest 2025, oldest 2022) . Low freshness flags an ageing evidence base — not that the answer is wrong.
Evidence over time
supporting contradicting refining / context Each dot is a study, placed by year and coloured by whether the linked claim supports or contradicts the answer. As the surveillance loop runs, claim revisions and new evidence will extend this timeline.
Choose a format (Vancouver default). Citing a version captures the evidence state on that date; this page shows the current version — see version history.
What changed in this version
Initial version (v1.0): 2 founding claims indexed from the lipedema pilot. The automated surveillance loop (new-article ingestion → supports / contradicts / refines) has not yet run.
Supporting claims
- SCR-LIP-000021 supporting
Lipedema and fibromyalgia frequently co-occur: a cross-sectional study found lipedema in 50% of women meeting ACR fibromyalgia criteria, with longer fibromyalgia diagnostic delay and younger menarche as risk factors.
DOI:10.1177/02683555251321042 - SCR-LIP-000022 supporting
Knee pain is a common musculoskeletal feature of lipedema, reported by 58.1% of women screening positive for lipedema in a Brazilian population study.
DOI:10.1590/1677-5449.202101981
Contradictory claims
- None indexed yet.
Major uncertainty
No controls without the comorbidity; directionality unclear; self-reported symptoms.
Version history
- SQ-LIP-000008 · v1.0 — 2026-05-30 — founding index (2 claims) · view this version
Key references
DOI:10.1177/02683555251321042 · DOI:10.1590/1677-5449.202101981